Nano-Selenium-Mediated Alterations in Lipid Profile, Liver and Renal Functions, and Protein Parameters in Male Lambs: An Experimental Study

The impact of nano-selenium supplementation on lipid metabolism, liver enzymes, renal function, and protein levels in male lambs was investigated this study during a 60-day period. Lambs were divided into two groups - control experimental, which administered nanoselenium orally at dosage 0.5 mg/ kg feed once day, daily. Each group consisted five lambs. According to the findings, cholesterol dropped significantly days 45 (P 0.01) 60 0.05), whereas triglyceride rose 15 30 0.01). Throughout trial, uric acid creatinine constant. At 60, aspartate aminotransferase (AST) decreased while alkaline phosphatase (ALP) declined 0.01 P 0.05, respectively). 30, albumin (0.05), but day saw an increase globulin 0.05). drop AST ALP might be sign that function has possibly improved. However, rise raise possibility taking supplements may affect how proteins are metabolized. findings concluded effects time-dependent. In addition possible improvements based changes levels, also noticed initial transient followed by decline levels. To determine time-dependent as well response objective study.